BMC Complement Altern Med 2018;18(1):224. J Ethnopharmacol. Leelarasamee, A., Trakulsomboon, S., Maunwongyathi, P., Somanabandhu, A., Pidetcha, P., Matrakool, B., Lebnak, T., Ridthimat, W., and Chandanayingyong, D. Failure of Phyllanthus amarus to eradicate hepatitis B surface antigen from symptomless carriers. UPC Code: 624917083262. Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Londhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Antioxidant activity of some polyphenol constituents of the medicinal plant Phyllanthus amarus Linn. Additional research on the benefits and side effects of chanca piedra should be encouraged. Etta HE, Udoh PB Asuquo BO et al. It is recommended not to use chancapiedra during pregnancy or breastfeeding. Chanca piedra benefits include its ability to ease digestive issues, prevent gallstones, boost liver health, and strengthen the immune system against bacterial infections. . Users and supplement manufacturers have established unofficial doses and guidelines based on trial and error. J Nat Prod 1996;59:196-9. Odetola, A. 2009;66(4):439-444. Royal Chanca Piedra Liver-Gall Bladder Support. Avoid it in pregnant and breastfeeding women. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1992;6-9. at what age can a child refuse visitation in utah; ventajas y desventajas de la terapia centrada en el cliente; humana otc pharmacy login; kindercare board of directors 2010;36(6):657-664. Jeena, K. J., Joy, K. L., and Kuttan, R. Effect of Emblica officinalis, Phyllanthus amarus and Picrorrhiza kurroa on N-nitrosodiethylamine induced hepatocarcinogenesis. In vitro antiplasmodial activity of callus culture extracts from fresh apical stems of Phyllanthus niruri: Part 1. This herb may act by [142, 148, 124, 143, 85, 84, 145, 146, 147]: In mice, chanca piedra improved memory and reversed amnesia [149]. Tamil, I. G., Dineshkumar, B., Nandhakumar, M., Senthilkumar, M., and Mitra, A. Some of these organizations include ConsumerLab, NSF International, and United States Pharmacopeia (USP). Herbs of the genus Phyllanthus in the treatment of chronic hepatitis B: observations with three preparations from different geographic sites. Balanced blood lipid levels are key to preventing heart disease [39, 60, 61, 62, 63, 64, 65, 66]. We do not aim to diagnose, treat, cure or prevent any illness or disease. Rao, M. V. and Alice, K. M. Contraceptive effects of Phyllanthus amarus in female mice. Sarkar MK, Kinter M Mazumder B et al. J Radiat.Res 2009;50(4):303-309. . Acta Pol.Pharm. Yao AN, Kamagat M, Amonkan AK, et al. Some animal research indicates that chanca piedra may help relax the blood vessels, which could lead to reductions in blood pressure (1). It's also purported to have anti-infection, anticancer, anti-inflammatory . 1999;20(4):164-166. 2014;9(4):515-7. Carlos received his PhD and MS from the Universidad de Sevilla. In addition to help people with gallbladder problems Chanca Piedra can help people with kidney stones. Okoli, C. O., Obidike, I. C., Ezike, A. C., Akah, P. A., and Salawu, O. People with type 1 or type 2 diabetes should also use this supplement with caution, as it may decrease blood sugar levels. Paris: Lavoisier Publishing, 1995. There are also no reported withdrawal symptoms. Learn more about causes and symptoms here. View abstract. Breast-feeding: There isn't enough reliable information to know if chanca piedra is safe to use while breast-feeding. Chanca piedra contains powerful antioxidants: rutin and quercitrin (a cousin of the better-known quercetin). Chanca Piedra. Chanca Piedra can sometimes have a rather strong taste so I avoid the tea in order to avoid the taste." Optimal Tincture Dosage. Chanca piedra is known by several names, including: The herb contains phytochemicals that may increase urine flow, destroy harmful bacteria and viruses, and reduce inflammation. Indian Journal of Pharmaceutical Sciences 2007;33-36. The Cochrane Library 1993;(1). The high phenolic content of chanca piedra has shown antioxidant activity, which has been found to support balanced blood sugar and normal blood pressure. . View abstract. View abstract. View abstract. Spanish for "stone crusher", Chanca Piedra is a plant that is traditionally used as a diuretic to help relieve mild urinary tract infections. Food Chemistry 2009;1405-1412. Here are 15 natural ways to lower your blood sugar levels. Consult with your healthcare provider before taking any new supplements. it's best to avoid it while pregnant, trying to get pregnant, or breastfeeding . It is used by folk healers in the Amazon and Ayurvedic practitioners alike. Theres no research on the long-term effects of chanca piedra, so it may be wise to limit the time you take the supplement to 12 weeks or less a duration that has been studied in humans (3). 10-11-2006;107(3):449-455. B., Antarkar, D. S., Deolalikar, R., and Antani, D. H. A two-stage clinical trial of Phyllanthus amarus in hepatitis B carriers: failure to eradicate the surface antigen. J-Clin-Epidemiol 1997;50(8S). 5. Antioxidant properties of the isolated flavonoids from the medicinal plant Phyllanthus niruri. Blumberg, B. S., Millman, I., Venkateswaran, P. S., and Thyagarajan, S. P. Hepatitis B virus and hepatocellular carcinoma--treatment of HBV carriers with Phyllanthus amarus. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Because it may affect kidney function, people with chronic kidney disease or other kidney problems should consult a healthcare professional before using chanca piedra. HIGH LEVELS OF CALCIUM IN THE URINE contribute to the growth of kidney stones in the gallbladder. Global Journal of Agricultural Sciences 2007;215-217. Efficacy of Phyllanthus niruri on improving liver functions in patients with alcoholic hepatitis: A double-blind randomized controlled trial. Chanca Piedra Powder: 1/2 - 1 tsp. Current Science 2003;84(4):529-533. Amariinic acid and related ellagitannins from Phyllanthus amarus. . You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. Find out if it can really clear your kidney stones, and learn more about its benefits and possible side effects. Raphael, K. R., Sabu, M. C., and Kuttan, R. Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential. View abstract. View abstract. Traditionally, this plant was used for abortions and may cause abnormalities with the fetus. Still, most of this research has been done in animal or test-tube studies. Furthermore, chanca piedra should not be taken by patients who are suffering from severe hypertension. Growth inhibitory effects of Phyllanthus niruri extracts in combination with cisplatin on cancer cell lines. There are studies that imply it has antiviral . Clinical studies are still limited, though. 16. View abstract. Select a condition to view a list of vitamins. The antiviral properties and the dense antioxidant content can control liver damage. Lee NY, Khoo WK, Adnan MA, et al. For kidney stones, chanca piedra is best taken as an extract at a dosage of 400-1000 mg/day. View abstract. Phytother.Res 2001;15(3):265-267. During and after surgery, blood sugar control can be interfered with. Acta Farmaceutica Bonaerense 2004;23:520-523. The term "Chanca Piedra" literally means "to break stone" which reflects its traditional use in treating kidney stones and gallstones. A dry extract of Phyllanthus niruri protects normal cells and induces apoptosis in human liver carcinoma cells. The plant has thin, leaf-covered branches. 4 Main Chanca Piedra Health Benefits. View abstract. Chanca piedra might lower blood sugar levels. The same was confirmed in numerous studies with diabetic rats [57, 73, 74, 75, 76, 48, 77, 62, 78, 63, 79, 66, 71]. Chanca piedra (Phyllanthus niruri) is a plant native to tropical coastal areas. McPartland JM. Still, you should limit the amount you take to the daily dose on the supplement label, as there could be safety concerns with high doses of chanca piedra that havent been studied yet. 2007;64(6):547-552. Indian J Exp.Biol. Moshi, M. J., Lutale, J. J., Rimoy, G. H., Abbas, Z. G., Josiah, R. M., and Swai, A. Foo LY. Iizuka, T., Nagai, M., Taniguchi, A., Moriyama, H., and Hoshi, K. Inhibitory effects of methyl brevifolincarboxylate isolated from Phyllanthus niruri L. on platelet aggregation. Etta H. Effects of Phyllanthus amarus on litter traits in albino rats. 2003;38(3):289-297. View abstract. Kidney stones can cause severe pain as well as other symptoms, including cloudy urine, pain during urination, and an urgent need to pee. Yet, theres no scientific evidence to support the use of chanca piedra specifically for gallstones. View abstract. Mahat MA, Patil BM. Its combination with anti-diabetes therapies (e.g. Sane RT, Kuber VV Chalissery MS et al. which enables users to obtain detailed information and reports based on their genome. And while this is promising, remember that the research is still preliminary. Celia A, Micali S Sighinolfi M et al. Ravikumar, Y. S., Ray, U., Nandhitha, M., Perween, A., Raja, Naika H., Khanna, N., and Das, S. Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source. Furthermore, the few clinical trials that were carried out had a small number of participants and some of their findings are debatable. WebMD does not provide medical advice, diagnosis or treatment. What did you take to control the pain that was considered safe . Effect of Phyllanthus amarus Schum. Journal of Medicinal and Aromatic Plant Sciences 1999;21(1):51. One health benefit of chanca piedra is that its antioxidants may improve fasting blood sugar levels in certain animals. Some animal studies have shown a decrease in uric acid levels in animals receiving chanca piedra supplements (1). J Ethnopharmacol. Chanca piedra can be taken with or without food. Acta Pol.Pharm. Chanca piedra is an herb that grows in tropical areas, like the rainforests of South America. 2006;176(3):1020-1022. Stomach ulcers occur when the thick layer of. Its a less expensive, over-the-counter alternative to prescription potassium citrate, an alkalizing agent thats commonly used to prevent acidic kidney stones. 2007;30(2):382-384. J Urol. Duke JA, Vasquez R. Amazonian Ethnobotanical Dictionary. However, the studies listed below should not be interpreted as supportive of any health benefit. The first thrives in humid, warm places and likes a bit of shade. I read that ox bile is what your supposed to take for digesting foods after . 2001;95(1):47-57. 2002;89(9):829-834. WebMD does not provide medical advice, diagnosis or treatment. Chanca piedra (Phyllanthus niruri) blocked an enzyme (5-reductase) involved in baldness and increased the animals hair growth. 2012;26(7):964-8. 2009;8(2):190-194. It may also slow blood clotting and increase your risk of bleeding. Redox.Rep. Chanca Piedra 500 mg Vegan Non-GMO Gluten-Free Supports a healthy liver An effective dose of a traditional remedy Promotes healthy kidneys and gallbladder Chanca Piedra is the Spanish name given to the herb Phyllanthus niruri which is native to the Amazonian region of South America. Sansalone S, Russo GI, Mondaini N, Cantiello F, Antonini G, Cai T. A combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts is able to improve sexual quality of life in patient with premature ejaculation. 6 benefits of chanca piedra. J Ethnopharmacol. Evaluation of hair growth promoting activity of Phyllanthus niruri. Complementary Medicine International 1996;3(2):40-42. J Med Virol. Consult your doctor before supplementing with chanca piedra if you are on medication. Since overactivity of this enzyme is thought to underlie baldness in men, chanca piedra might turn out to be a targeted remedy for hair re-growth [156]. Dirjomuljono, M., Kristyono, I., Tjandrawinata, R. R., and Nofiarny, D. Symptomatic treatment of acute tonsillo-pharyngitis patients with a combination of Nigella sativa and Phyllanthus niruri extract. Indian J Exp Biol 1995; 33:861-4. Pharmaceutical Biology (Netherlands) 2004;42:512-518. 11-1-2007;114(2):169-173. View abstract. View abstract. The nursing mother should take the lowest dose possible. View abstract. Asian Pac.J Cancer Prev. Although there is no clinical evidence, chanca piedra lowered both male and female fertility in mice [1, 162, 163, 164]. Theres not enough research available to suggest that chanca piedra overdose is possible. Chanca piedra has the potential to interact with several medications, including: Chanca piedra supplements in any form tea, extract, or pills should be kept in a cool, dry place where they wont be exposed to excessive moisture or temperature changes. Pure Natural and Organic. Virus Res 2011;158(1-2):89-97. The herb also appears to be helpful for treating hepatitis B, an inflammatory viral infection of the liver at least in animal and test-tube studies (1). They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1999;12-31. View abstract. Furthermore, chanca piedra is not safe for pregnant women and can interact with various drugs. If you choose to take chanca piedra, you should buy a supplement that has been independently verified for quality by a third party organization. Boca Raton, FL: CRC Press, LLC 1994. Efficacy of Phyllanthus amarus treatment in acute viral hepatitis A, B and non A non B: an open clinical trial. Below is a summary of the existing animal and cell-based research, which should guide further investigational efforts. It supports a healthy cholesterol balance and may reduce hypertension, helping to support heart health. You should also watch for signs of hypoglycemia (low blood sugar). Side effects reported in one human study using a chanca piedra infusion included: Additional health risks of chanca piedra may include: Chanca piedra may lower blood sugar levels, which means it might affect blood sugar control during and after surgery. Latest from brand. We understand that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. Keep in mind that natural products are not always necessarily safe and dosages can be important. What follows is a short list of nine of the more important benefits from this ancient herbal treatment: 1. Kerala Journal of Veterinary Science 1989;20(1):77-80. Niu, J. Put a bookmark here and read the information available on this page. Although there is no clinical evidence, chanca piedra lowered both male and female fertility in mice [1, 162, 163, 164]. This also holds true for those trying to conceive. Taking chanca Piedra along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Further clinical research is required. Munshi, A., Mehrotra, R., Ramesh, R., and Panda, S. K. Evaluation of anti-hepadnavirus activity of Phyllanthus amarus and Phyllanthus maderaspatensis in duck hepatitis B virus carrier Pekin ducks. View abstract. Asian Journal of Food and Agro-Industry 2009;2(3). Pharm.Biol. Harikumar, K. B., Kuttan, G., and Kuttan, R. Inhibition of viral carcinogenesis by Phyllanthus amarus. Consult your doctor before supplementing with chanca piedra if you are on medication. While there is no regulatory or consensus-based definition for paleo when referring to diets, we use the term "paleo-friendly" to describe products that consist of lean meats and seafood, fruits and . To sum it up, chanca piedra may fight incredibly diverse types of infections. Common home remedies for kidney stones include drinking different fluids to help flush your stones out and prevent new ones. It may also help you urinate more (2). However, these 8 dietary strategies can help make sure you don't get another one. SelfDecode is a personalized health report service, In vitro study on alpha-amylase inhibitory activity of an Indian medicinal plant, Phyllanthus amarus. He says I am real sick and not getting better so he is worried. Notka, F., Meier, G. R., and Wagner, R. Inhibition of wild-type human immunodeficiency virus and reverse transcriptase inhibitor-resistant variants by Phyllanthus amarus. J Pharm Pharmacol. Failure of New Zealand hepatitis B carriers to respond to Phyllanthus amarus. Murugaiyah, V. and Chan, K. L. Determination of four lignans in Phyllanthus niruri L. by a simple high-performance liquid chromatography method with fluorescence detection. Effect of Phyllanthus amarus on breeding efficiency of female albino rats. In one human study that showed improvements in kidney stones, the daily dosage was 4.5 grams of powdered chanca piedra for 12 weeks (3). Footer Yes! View abstract. Treats kidney stones, gall stones and urinary tract issues. . Therapeutic Research Faculty 2020. The English translation for Chanca piedra is stone crusher.' Recent scientific evidence validates this historical use. Naik, A. D. and Juvekar, A. R. Effects of alkaloidal extract of Phyllanthus niruri on HIV replication. In Ayurveda, chanca piedra has been used for [1, 5, 9, 10]: Chanca piedra is also used in cosmetic, dental, and skincare products, including hair dye, face creams, and toothpaste [11]. Because chanca piedra is not approved by the FDA for any conditions, there is no official dose. Beneficial effects of Phyllanthus amarus for chronic hepatitis B, not confirmed. Chanca piedra increases the risk of bleeding and slows blood clot making. All chanca piedra species are abundant in bioactive components, which carry their purported health benefits. Naaz F, Javed A Abdin MZ. You may try chanca piedra as a supportive measure if your doctor thinks it may help in your case, but never use it in place of what your doctor recommends or prescribes. Larger, more robust clinical trials are needed. Animal and cell-based studies reveal chanca piedra contains powerful antioxidant, anti-inflammatory, anti-cancer, and antibacterial compounds. CHANCA PIEDRA ALSO KNOWN AS "STONE CRUSHER" FROM PLATNIUM NATURALS.Originally found growing in the Amazon rain forest, Chanca Piedra was named by the native Indians and noted for its ability to help dissolve kidney and gallstones. Our website services, content, and products are for informational purposes only. In turn, it might boost acetylcholine levels in the brain, which would be useful to people with Alzheimers disease [151, 152]. J Hepatol. According to some claims, chanca piedra may have several beneficial effects on different body systems. When using it, monitor your blood sugar regularly if you have diabetes. Therefore, its best to avoid it while pregnant, trying to get pregnant, or breastfeeding. View abstract. Joe Cohen flipped the script on conventional and alternative medicine and it worked. Sowjanya K, Girish C, Bammigatti C, Prasanna Lakshmi NC. View abstract. 1985;14(1):41-44. The entire plant including the leaves, stems, and flowers is used to make chanca piedra supplements. 5-10 drops of Chanca Piedra tincture in 8 oz of filtered water 2 or 3 times a day. View abstract. Chanca-Piedra tea is known to fight kidney stones and kidney cramps and to clean and stimulate the organs. Overall, it may protect the liver by [30, 31, 52, 39, 40, 53, 54, 55, 56]: To sum it up, chanca piedra may help combat viral hepatitis, but its probably not superior to conventional antivirals. View abstract. While many of the items on Etsy are handmade, you'll also find craft supplies, digital items, and more. Syamasundar, K. V., Singh, B., Thakur, R. S., Husain, A., Kiso, Y., and Hikino, H. Antihepatotoxic principles of Phyllanthus niruri herbs. View abstract. The herb is alkaline, so it may help prevent acidic kidney stones. Best known for helping to eliminate kidney stones and gall stones, it is also traditionally used in Andean medical systems and around the world . and its protective mechanism on paracetamol hepatotoxicity in rats. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare providers because of something you have read on SelfHacked. African Journal of Pharmacy and Pharmacology 2010;226-230. Urol.Res 2004;32(5):362-366. Chanca piedra might slow blood clotting. Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. Furthermore, in cells, it blocked the replication of hepatitis C and hepatitis B, HIV-1, herpes virus (HSV-1) and dengue virus [55, 112, 113, 114, 115, 116, 117, 118, 56, 119, 120, 121, 122, 123]. Southeast Asian J Trop.Med Public Health 2007;38(4):609-615. This herb may also counter the effects of norepinephrine. View abstract. In reality, two different species Phyllanthus niruri and Phyllanthus amarus are both referred to as chanca piedra or stone breaker [2, 3]. May Boost Liver Health. Biol.Pharm.Bull. View abstract. Having high blood sugar levels is a common issue for people with diabetes and prediabetes. 2011;185(1):323-328. Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention. Animal and Cell Research (Lack of Evidence). In large . U.S. Food and Drug Administration.Warning Letter: Herbs America, Inc. MARCS-CMS 545913.. Abhyankar G, Suprasanna P Pandey BN et al. Indian J Gastroenterol. Healthline Media does not provide medical advice, diagnosis, or treatment. Paying attention to what our bodies try to tell us, is the first step in preventing serious health issues, in this case kidney stones. View abstract. Urol.Res 2006;34(6):351-357. & Thonn. Chanca piedra may help balance out these levels and prevent gout attacks. No evidence supports the use of chanca piedra for any of the conditions listed in this section. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Chanca Piedra is a medicinal herb believed to assist with various ailments related to the digestive system, liver, and kidneys. Chanca Piedra or "stone breaker" is well known for successfully treating kidney stones - it's where the herb got its name. West African Journal of Pharmacology and Drug Research 2007;42-50. Dimensions: 5.1 x 5.1 x 9.7 cm, 0.07 kg. Clark BC, Georgekutty J, Berul CI. There's no one sure way to prevent kidney stones, especially if you have a family history of the condition. Chanca Piedra 100 caps, chanca piedra leaf, Organic Stone breaker, kidney Liver Calculos Renales chancapiedra herbal capsules !!! Notka, F., Meier, G., and Wagner, R. Concerted inhibitory activities of Phyllanthus amarus on HIV replication in vitro and ex vivo. Myint MM, Than MA Lwin KK et al. In rats and mice, chanca piedra prevented stomach damage and ulcers caused by various harmful substances; it also decreased stomach inflammation [84, 52, 85, 86, 87, 88]. Mustofa, Sholikhah, E. N., and Wahyuono, S. In vitro and in vivo antiplasmodial activity and cytotoxicity of extracts of Phyllanthus niruri L. herbs traditionally used to treat malaria in Indonesia. 2013;8(4):493-6. and for pregnant or breastfeeding women. Murugaiyah, V. and Chan, K. L. Antihyperuricemic lignans from the leaves of Phyllanthus niruri. Hypoglycemic Effect of an Aqueous Extract of Phyllanthus sellowianus ("sarandi blanco") in C57BL/Ks mice. Kidney stones: Chanca piedra is also called a "stone breaker" because it can treat kidney stones. Moshi MJ, Uiso FC Mahunnah RL et al. When used as a natural remedy for kidney stones it goes by the popular name of "stone breaker". Indian J Pharmacol 2021;53(6):448-456. and Thonn.). Healing and Rejuvenation: It's valued for its healing . 4. He strongly believes that scientific literacy is crucial to maintain a healthy lifestyle and avoid falling for scams. The phenolic component that it has, have been identified as a strong antioxidant. In Africa, on the other hand, theyre deemed useful for malaria and wound healing [2, 3]. View abstract. 4.3 out of 5 stars . Kidney Stones. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Integr.Cancer Ther. Eur J Clin Invest 1996;26(12):1069-1076. Animal and test-tube studies show that the herb may also help treat hepatitis B, an inflammatory viral infection of the liver. Jonathan Ritter, PharmD, PhD (Pharmacology), Sexually transmitted diseases (syphilis, gonorrhea), Lignans (phyllanthin, hypophyllanthin), which have, May protect the liver, digestive system, and heart, May lower inflammation, pain, and oxidative stress, Lack of research for many traditional uses, Blocking the growth and the clustering of salts that form kidney stones. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. View abstract. Chanca piedra is not approved by the U.S. Food and Drug Administration to treat any condition. $47.16 $ 47. World J Gastroenterol. Int J Clin Pharmacol.Ther 2008;46(6):295-306. Their reviews do not represent the opinions of SelfHacked. Health 2010;511-512. While this effect can help manage hyperglycemia (high blood sugar) . It is considered as an anti-inflammatory and a pain blocker similar to morphine but without side effects. Chanca Piedra has been proven in scientific . In the studies that have been done on chanca piedra, there doesnt appear to be any risks to stopping the supplement suddenly. A randomized, prospective, long-term study. View abstract. View abstract. Kumar NG, Nair AN Raghunandanan VR et al. Narendranathan, M., Remla, A., Mini, P. C., and Satheesh, P. A trial of Phyllanthus amarus in acute viral hepatitis. In Brazil, people call it Quebra Pedra, which means stone breaker in Portuguese. et Thonn. Monitor yourblood sugar levels when taking Chanca Piedra since it might lower bloodsugar . Hepatoprotection by Phyllanthus amarus and Phyllanthus debilis in CCl4-induced liver dysfunction.