The acidity may also cause tooth decay in some individuals. Drinking large quantities can lead to feeling uncomfortably full and bloated. Grapefruit juice products can also have large amounts of added sugars depending on the product and brand. The news is based on a review that has highlighted grapefruit-medication interactions that can cause serious side effects. If too much is consumed in one sitting, it can play havoc on the stomach and gastroesophageal flap, which is responsible for heartburn and acid reflux. Plus, if you drink sweetened grapefruit juice, keep in mind that sugar-sweetened drinks are leading contributors to obesity. Do not take other medicines unless … Her work has appeared in "Reader‚Äôs Digest," "Balance," pharmaceutical and natural health newsletters and on websites such as QualityHealth.com. Grapefruit juice, which is filled with vitamin C and potassium, can be part of a healthy diet. Other common drugs with potential serious side effects are antidepressants, antibiotics, antihistamines, antifungals, and cancer fighting drugs. Use of this web site constitutes acceptance of the LIVESTRONG.COM Liver enzyme test results, especially the ALT and AST, may increase when you're on Lipitor. One of the well-known dangers of grapefruit juice is its ability to interact with numerous medications, even in small amounts. Atorvastatin interacts with grapefruit juice if you drink large quantities (more than 1.2 litres daily), but an occasional glass is thought to be safe. Weight gain is the result of consuming too many calories and not getting enough exercise. Grapefruit is such a powerful natural nutrient that it can actually act as a drug in the body. Gastroesophageal reflux, or heartburn, occurs when the lower esophageal sphincter between the stomach and esophagus is weak or doesn't function properly. Grapefruit juice can go down easy and quickly for a grapefruit aficionado. If patients on this drug eat grapefruit or drink grapefruit juice, it may cause torsade de pointes, a serious, often fatal, heart problem. Copyright © Your email address will not be published. This also has side effects which are lesser known but we all need to be aware of these. Copyright Policy If too much is consumed in one sitting, it can play havoc on the stomach and gastroesophageal flap, which is responsible for heartburn and acid reflux. Whenever possible, drink grapefruit juice through a straw to protect your teeth. As a result, it allows acid to flow back up from the stomach into the esophagus. That's because the studies showing dangerous effects used massive amounts of furanocoumarins, the amount found in a quart or more of the juice. (5) Grapefruit, grapefruit juice, and related oils and extracts can also interact with certain medications. Side effects may include muscle pain, fever, headache, edema and abdominal pain and can increase if grapefruit is a part of your diet 2. However, you can have too much of a good thing. The single most important side effect to be aware of is the impact on your kidneys. What's more, eating half a grapefruit is even less risky than drinking grapefruit juice, since it takes several fruits to make a single glass of juice. Kay Uzoma has been writing professionally since 1999. Both juice and the fruit itself can significantly slow down the body’s ability to metabolize many drugs. The fruit and its juice are rich in nutrients, including pectin fiber, vitamin C and other antioxidants such as flavonoids. Be astute to any sensitivity that may occur. The fruit and its juice are rich in nutrients, including pectin fiber, vitamin C and other antioxidants such as flavonoids. A 6-year study done on men between the age of 40 and 75 years found that having 8 ounces of grapefruit juice every day increased the risk of kidney stones by about 37%. It is your responsibility to bring it to their attention. But, according to the FDA, you might want to avoid drinking grapefruit juice if you are taking certain prescription drugs and over-the-counter drugs to avoid harmful side effects.Speak with your doctor or pharmacist about possible interactions. side effects of drinking too much grapefruit juice. 13 However, a short-term study found that having grapefruit juice regularly helped in flushing out citrates, calcium, and magnesium, thus reducing the risk of stone formation. diagnosis or treatment. Leaf Group Ltd. She is a former editor for a national Canadian magazine and holds a Bachelor of Arts in political science from York University. any of the products or services that are advertised on the web site. Avoid the use of toxic and offensive language. Someone prone to these symptoms should consume smaller portions of grapefruit at a time. Pheromones are also managed by the CYP3A4 enzyme. Trusted Source. There is a long list of prescription drugs that interact with grapefruit. If you suffer from IBS, you might not be able to enjoy the benefits of grapefruit. Other drugs grapefruit juice might affect include immune suppressants and some heart disease medications such as calcium channel blockers. … Your email address will not be published. Eating grapefruit or drinking grapefruit juice while taking these medications can lead to higher levels of them in your blood — and more side effects. As little as eight ounces can make an impact in drug toxicity. This fruit may also cause digestive distress when consumed in excess. Effects are antidepressants, antibiotics, antihistamines, antifungals, and related oils and extracts also! Cyp3A4 in the body ’ s ability to interact with grapefruit there is a hybrid of LIVESTRONG... 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